• Serum miR371 in testicular germ cell cancer before and after orchiectomy, assessed by digital-droplet PCR in a prospective study 

      Myklebust, Mette Pernille; Thor, Anna; Rosenlund, Nina Benedikte; Gjengstø, Peder; Karlsdottir, Åsa; Brydøy, Marianne; Bercea, Bogdan Stefan; Olsen, Christian; Johnson, Ida; Berg, Mathilde I.; Langberg, Carl; Andreassen, Kristine; Kjellman, Anders; Haugnes, Hege Sagstuen; Dahl, Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-02)
      MicroRNA-371a-3p (miR371) has been suggested as a sensitive biomarker in testicular germ cell cancer (TGCC). We aimed to compare miR371 with the classical biomarkers α-fetoprotein (AFP) and β-human chorionic gonadotropin (hCG<sub>β</sub>). Overall, 180 patients were prospectively enrolled in the study, with serum samples collected before and after orchiectomy. We compared the use of digital droplet ...
    • Sperm counts and endocrinological markers of spermatogenesis in long-term survivors of testicular cancer 

      Brydøy, Marianne; Fosså, Sophie Dorothea; Klepp, Olbjørn; Bremnes, Roy M.; Wist, Erik; Bjøro, Trine; Wentzel-Larsen, Tore; Dahl, Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-11-20)
      Background: The objective of this study was to assess markers of spermatogenesis in long-term survivors of testicular cancer (TC) according to treatment, and to explore correlations between the markers and associations with achieved paternity following TC treatment.<p> <p>Methods: In 1191 TC survivors diagnosed between 1980 and 1994, serum-follicle stimulating hormone (s-FSH; n ¼ 1191), s-inhibin ...
    • Thromboembolic events after high-intensity training duringcisplatin-based chemotherapy for testicular cancer: Casereports and review of the literature 

      Thorsen, Lene; Haugnes, Hege Sagstuen; Fosså, Sophie Dorothea; Brydøy, Marianne; Tandstad, Torgrim; Wisløff, Torbjørn; Gjerset, Gunhild Maria; Edvardsen, Elisabeth; Larsen, Karl-Otto; Sandset, Per Morten; Henriksson, Carola; Raastad, Truls; Negaard, Helene Francisca Stigter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-11)
      The randomized “Testicular cancer and Aerobic and Strength Training trial” (TAST‐trial) aimed to evaluate the effect of high‐intensity interval training (HIIT) on cardiorespiratory fitness during cisplatin‐based chemotherapy (CBCT) for testicular cancer (TC). Here, we report on an unexpected high number of thromboembolic (TE) events among patients randomized to the intervention arm, and on a review ...